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General section on renal cell tumors
== Contributors ==
Yajuan J. Liu PhD, FACMG
== General section on renal cell tumors ==
Renal cell tumors comprise a heterogeneous group of tumors arising from the nephron, with diverse histological morphology, genetic alterations, and clinical behavior. The 2016 WHO classification of renal cell tumors (listed below) is primarily based on cytoplasmic features, architectural features, anatomic location of tumors, correlation with a specific renal disease background, and molecular alterations that are pathognomonic for RCC subtypes or familial predisposition syndromes.
Renal cell tumors comprise a heterogeneous group of tumors arising from the nephron, with diverse histological morphology, genetic alterations, and clinical behavior. The 2016 WHO classification of renal cell tumors (listed below) is primarily based on cytoplasmic features, architectural features, anatomic location of tumors, correlation with a specific renal disease background, and molecular alterations that are pathognomonic for RCC subtypes or familial predisposition syndromes.