Compendium of Cancer Genome Aberrations

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Gene-Specific Template (Updated 9-28-21) (view source)

Revision as of 13:19, 28 September 2021

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{{Under Construction}}
 
{{Under Construction}}
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See '''[https://ccga.io/index.php/Author_Instructions ''Author Instructions'']''' and '''[https://ccga.io/index.php/How_to_Curate_a_Gene_Page ''How to Curate a Gene Page]'''
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See '''[https://ccga.io/index.php/Author_Instructions ''Author Instructions'']''' and '''[https://ccga.io/index.php/How_to_Curate_a_Gene_Page ''How to Curate a Gene Page'']'''
    
==Primary Author(s)*==
 
==Primary Author(s)*==
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__TOC__
 
__TOC__
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==Synonyms==
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==Gene Characteristics==
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{| class="wikitable"
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|'''Synonyms'''
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|EXAMPLE: Tumor protein p53, 'LFS1, p53, BCC7, TRP53
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|'''Cytoband'''
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|EXAMPLE: 17p13.1
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|'''Genomic Coordinates'''
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|EXAMPLE: chr17:7,668,402-7,687,538 [GRCh38/hg38]
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Put your text here
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EXAMPLE: chr17:7,571,720-7,590,868 [GRCh37/hg19]
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EXAMPLE: Tumor protein p53, 'LFS1, p53, BCC7, TRP53
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|-
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|'''Gene/Protein Native Function'''
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|EXAMPLES: Growth factor, DNA repair, Apoptosis
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==Genomic Location==
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==Gene in Cancer Overview==
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'''Cytoband:''' Put your text here. EXAMPLE: 17p13.1
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'''Genomic Coordinates:'''
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Put your text here
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EXAMPLE: chr17:7,571,720-7,590,868 [hg19]
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EXAMPLE: chr17:7,668,402-7,687,538 [hg38]
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==Cancer Category/Type==
      
Put your text here
 
Put your text here
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==Gene Overview==
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==Clinical Cancer Associations (Somatic)==
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{| class="wikitable"
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|'''Tumor Type'''
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|'''Alteration Type(s)'''
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|'''Diagnostic Significance (Yes, No or  Unknown)'''
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|'''Prognostic Significance (Yes, No or  Unknown)'''
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|'''Therapeutic Significance (Yes, No or  Unknown)'''
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|-
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|EXAMPLE:  Chronic  Myeloid Leukemia (CML), BCR-ABL1 Positive (link  to internal page through this name)
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|EXAMPLES:  Copy Number Loss, Copy Number Gain, LOH, Loss-of-Function Mutation,  Gain-of-Function Mutation, Translocation/Fusion, Expression Changes  (Biomarker), Somatic Hypermutation
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==Clinical Cancer Associations (Germline)==
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{| class="wikitable"
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==Common Alteration Types==
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|'''Tumor Type'''
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|'''Alteration Type(s)'''
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Put your text here and fill in the table with an X where applicable
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|'''Diagnostic Significance (Yes, No or  Unknown)'''
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|'''Prognostic Significance (Yes, No or  Unknown)'''
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{| class="wikitable sortable"
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|'''Therapeutic Significance (Yes, No or  Unknown)'''
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|-
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|EXAMPLE:    Myeloid  Neoplasms with Germline ANKRD26 Mutation (link to  internal page through this name)
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|EXAMPLES:  Copy Number Loss, Copy Number Gain, LOH, Loss-of-Function Mutation,  Gain-of-Function Mutation, Translocation/Fusion,  
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!Copy Number Loss!!Copy Number Gain!!LOH!!Loss-of-Function Mutation!!Gain-of-Function Mutation!!Translocation/Fusion
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|EXAMPLE: X||EXAMPLE: X||EXAMPLE: X||EXAMPLE: X||EXAMPLE: X||EXAMPLE: X
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==Internal Pages==
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==Association with Other Diseases==
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Put your links here (use "Link" icon at top of page)
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Put your text here
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==External Links==
 
==External Links==
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14) LOVD(3) - Leiden Open Variation Database
 
14) LOVD(3) - Leiden Open Variation Database
 
15) TICdb - database of Translocation breakpoints In Cancer
 
15) TICdb - database of Translocation breakpoints In Cancer
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16) GeneReviews, and
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16) GeneReviews,  
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17) Any gene-specific databases.
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17) ClinGen, and 18) Any gene-specific databases.
    
EXAMPLES (these may be filled in already)
 
EXAMPLES (these may be filled in already)
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'''[http://www.omim.org/entry/165215 ''MECOM'' by OMIM]''' - compendium of human genes and genetic phenotypes
 
'''[http://www.omim.org/entry/165215 ''MECOM'' by OMIM]''' - compendium of human genes and genetic phenotypes
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'''[https://databases.lovd.nl/shared/genes/MECOM ''MECOM'' by LOVD(3)]''' - Leiden Open Variation Database
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'''[https://databases.lovd.nl/shared/genes/MECOM ''MECOM'' by LOVD(3)]''' - Leiden Open Variation Database
    
'''[http://www.unav.es/genetica/TICdb/results.php?hgnc=MECOM ''MECOM'' by TICdb]''' - database of Translocation breakpoints In Cancer
 
'''[http://www.unav.es/genetica/TICdb/results.php?hgnc=MECOM ''MECOM'' by TICdb]''' - database of Translocation breakpoints In Cancer
    
'''[https://www.ncbi.nlm.nih.gov/books/NBK1311/ GeneReviews]''' - information on Li Fraumeni Syndrome
 
'''[https://www.ncbi.nlm.nih.gov/books/NBK1311/ GeneReviews]''' - information on Li Fraumeni Syndrome
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==Additional Information==
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Put your text here
    
==References==
 
==References==
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<references />
 
<references />
 
===EXAMPLE Book===
 
===EXAMPLE Book===
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#Arber DA, et al., (2017). Acute myeloid leukaemia with recurrent genetic abnormalities, in World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues, Revised 4th edition. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Arber DA, Hasserjian RP, Le Beau MM, Orazi A, and Siebert R, Editors. IARC Press: Lyon, France, p129-171.
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=== EXAMPLE Internet Resource ===
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#Arber DA, et al., (2017). Acute myeloid leukaemia with recurrent genetic abnormalities, in World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues, Revised 4th edition. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Arber DA, Hasserjian RP, Le Beau MM, Orazi A, and Siebert R, Editors. IARC Press: Lyon, France, p130-149.
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# author name(s).  Date (if possible). page title, website title, web address, and date accessed.
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# Cingam, S. R. and Koshy, N.V. (2017). Cancer, Leukemia, Promyelocytic, Acute (APL, APML). https://www.ncbi.nlm.nih.gov/books/NBK459352/ Accessed August 3, 2018.
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===EXAMPLE Internet Resource===
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#author name(s).  Date (if possible). page title, website title, web address, and date accessed.
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#Cingam, S. R. and Koshy, N.V. (2017). Cancer, Leukemia, Promyelocytic, Acute (APL, APML). https://www.ncbi.nlm.nih.gov/books/NBK459352/ Accessed August 3, 2018.
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== Notes ==
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==Notes==
 
<nowiki>*</nowiki>Primary authors will typically be those that initially create and complete the content of a page.  If a subsequent user modifies the content and feels the effort put forth is of high enough significance to warrant listing in the authorship section, please contact the CCGA coordinators (contact information provided on the homepage).  Additional global feedback or concerns are also welcome.
 
<nowiki>*</nowiki>Primary authors will typically be those that initially create and complete the content of a page.  If a subsequent user modifies the content and feels the effort put forth is of high enough significance to warrant listing in the authorship section, please contact the CCGA coordinators (contact information provided on the homepage).  Additional global feedback or concerns are also welcome.
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